Sodium Reduction and Its Effect on Food Safety, Food Quality, and Human Health
Marjorie Ellin Doyle
Authors are with Food Research Inst., Univ. of Wisconsin–Madison, 1550 Linden Drive, Madison, WI 53706, U.S.A. Direct inquiries to author Doyle (E-mail: [email protected] ).
Search for more papers by this authorKathleen A. Glass
Authors are with Food Research Inst., Univ. of Wisconsin–Madison, 1550 Linden Drive, Madison, WI 53706, U.S.A. Direct inquiries to author Doyle (E-mail: [email protected] ).
Search for more papers by this authorMarjorie Ellin Doyle
Authors are with Food Research Inst., Univ. of Wisconsin–Madison, 1550 Linden Drive, Madison, WI 53706, U.S.A. Direct inquiries to author Doyle (E-mail: [email protected] ).
Search for more papers by this authorKathleen A. Glass
Authors are with Food Research Inst., Univ. of Wisconsin–Madison, 1550 Linden Drive, Madison, WI 53706, U.S.A. Direct inquiries to author Doyle (E-mail: [email protected] ).
Search for more papers by this authorAbstract
ABSTRACT: Sodium is an essential nutrient with important functions in regulating extracellular fluid volume and the active transport of molecules across cell membranes. However, recent estimates from NHANES III (Third National Health and Nutrition Examination Survey) data show that over 95% of men and over 75% of women exceed the recommended daily tolerable upper intake of sodium. Since these high levels of dietary sodium are associated with a high prevalence of hypertension, prehypertension and, possibly, other adverse effects on health, many national and international health organizations recommend that sodium intake be significantly decreased. Traditionally, salt (sodium chloride) has been used as a food preservative that kills or limits the growth of foodborne pathogens and spoilage organisms by decreasing water activity. Salt also performs other important functions in foods by adding flavor and masking bitter tastes, controlling growth of yeast and fermentative bacteria, and promoting binding of proteins and other components in foods to achieve desired textures. Many processed foods contain high levels of salt and several countries have developed national programs for significantly reducing the sodium chloride content in many processed foods and encouraging a decrease in discretionary salt use. This review considers published data on the apparent adverse health effects of excess salt intake as well as the important functions of salt in different foods and possible strategies for reducing sodium levels in processed foods while still producing safe foods that consumers find acceptable.
References
- Adrogué HJ, Madias NE. 2008. Sodium and potassium in the pathogenesis of hypertension. N Engl J Med 356: 1966–78.
- Alderman MH. 2006. Evidence relating dietary sodium to cardiovascular disease. J Am Coll Nutr 25: 256S–61S.
- Aliño M, Grau R, Baigts D, Barat JM. 2009. Influence of sodium replacement on the salting kinetics of pork loin. J Food Engr 95: 551–7.
- Andersen L, Rasmussen LB, Larsen EH, Jakobsen J. 2009. Intake of household salt in a Danish population. Eur J Clin Nutr 63: 598–604.
- Anonymous. 2000. Food additives for use in meat and poultry products: sodium diacetate, sodium acetate, sodium lactate and potassium lactate. Fed Register 65: 3121–3.
- Anonymous. 2003. Control of Listeria monocytogenes in ready-to-eat meat and poultry products; final rule. Fed Register 68: 34207–55.
- Askar A, Elsamahy SK, Shehata HA, Tawfik M. 1993. Pasterma and beef bouillon—the effect of substituting KCl and K lactate for sodium chloride. Fleischwirtschaft 73: 289–92.
- Baird-Parker AC. 1990. The staphylococci: an introduction. J Appl Bacteriol 61: S1–8.
- Beaglehole R, Ebrahim S, Reddy S, Voute J, Leeder S. 2007. Prevention of chronic diseases: a call to action. Lancet 370: 2152–7.
- Beauchamp GK, Mennella JA. 2009. Early flavor learning and its impact on later feeding behavior. J Pediatr Gastroenterol Nutr 48: S25–30.
- Beer-Borst S, Costanza MC, Pechere-Bertschi A, Morabia A. 2009. Twelve-year trends and correlates of dietary salt intakes for the general adult population of Geneva, Switzerland. Eur J Clin Nutr 63: 155–64.
- Benkeblia N. 2004. Antimicrobial activity of essential oil extracts of various onions (Allium cepa) and garlic (Allium sativum). Lebensm Wiss Technol 37: 263–8.
- Betts G, Everis L, Betts R. 2007. Microbial issues in reducing salt in food products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 174–200.
- Bidlas E, Lambert RJW. 2008. Comparing the antimicrobial effectiveness of NaCl and KCl with a view to salt/sodium replacement. Int J Food Microbiol 124: 98–102.
- Boziaris IS, Skandamis PN, Anastasiadi M, Nychas GJE. 2007. Effect of NaCl and KCl on fate and growth/no growth interfaces of Listeria monocytogenes Scott A at different pH and nisin concentrations. J Appl Microbiol 102: 796–805.
- Brown IJ, Tzoulaki I, Candeias V, Elliott P. 2009. Salt intakes around the world: implications for public health. Int J Epidemiol 38: 791–813.
- Buck VE, Barringer SA. 2007. Factors dominating adhesion of NaCl onto potato chips. J Food Sci 72: E435–41.
- Burt S. 2004. Essential oils: their antibacterial properties and potential applications in foods—a review. Int J Food Microbiol 94: 223–53.
- Buzby JC, Wells HF, Axtman B, Mickey J. 2009. Supermarket loss estimates for fresh fruit, vegetables, meat, poultry, and seafood and their use in the ERS loss-adjusted food availability data. Econ Inform Bull 44. U.S. Dept. of Agriculture, Econ Res Serv.
- Carbone LD, Bush AJ, Barrow KD, Kang AH. 2003. The relationship of sodium intake to calcium and sodium excretion and bone mineral density of the hip in postmenopausal African-American and Caucasian women. J Bone Miner Metab 21: 415–20.
- Cauvain SP. 2007. Reduced salt in bread and other baked products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 283–95.
- [CDCP] Centers for Disease Control and Prevention. 2009. Application of lower sodium intake recommendations to adults—United States, 1999–2006. Morbid Mortal Weekly Rep 58: 281–3.
- Charlton KE, MacGregor E, Vorster NH, Levitt NS, Steyn K. 2007. Partial replacement of NaCl can be achieved with potassium, magnesium and calcium salts in brown bread. Int J Food Sci Nutr 58: 508–21.
- Chen J, Gu DF, Huang JF, Rao DC, Jaquish CE, Hixson JE, Chen CS, Chen JC, Lu FH, Hu DS, Rice T, Kelly TN, Hamm LL, Whelton PK, He J. 2009. Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study. Lancet 373: 829–35.
- Cheville AM, Arnold KW, Buchrieser C, Cheng CM, Kaspar CW. 1996. rpoS regulation of acid, heat, and salt tolerance in Escherichia coli O157:H7. Appl Environ Microbiol 62: 1822–4.
-
Chipley JR. 2005. Sodium benzoate and benzoic acid. In: PM Davidson,
JN Sofos,
AL Branen, editors. Antimicrobials in food.
New York
: Taylor & Francis. p
11–48.
10.1201/9781420028737.ch2 Google Scholar
- Christian JHB. 2000. Drying and reduction of water activity. In: BM Lund, TC Baird-Parker, GW Gould, editors. The microbiological safety and quality of food. Gaithersburg , Md. : Aspen Publishers. p 146–74.
- Cobcroft M, Tikellis K, Busch JLHC. 2008. Salt reduction—a technical overview. Food Australia 60: 83–6.
- Cohen HW, Hailpern SM, Alderman MH. 2008. Sodium intake and mortality follow-up in the third National Health and Nutrition Examination Survey (NHANES III). J Gen Intern Med 23: 1297–302.
- Cook NR, Cutler JA, Obarzanek E, Buring JE, Rexrode KM, Kumanyika SM, Appel LJ, Whelton PK. 2007. Long-term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention. Brit Med J 334: 885–92.
- Cook NR, Obarzanek E, Cutler JA, Buring JE, Rexrode KM, Kumanyika SK, Appel LJ, Whelton PK. 2009. Joint effects of sodium and potassium intake on subsequent cardiovascular disease. The Trials of Hypertension Prevention follow-up study. Arch Intern Med 169: 32–40.
- Dall TM, Fulgoni VL, Zhang YD, Reimers KJ, Packard PT, Astwood JD. 2009a. Potential health benefits and medical cost savings from calorie, sodium, and saturated fat reductions in the American diet. Am J Health Promot 23: 412–22.
- Dall TM, Fulgoni VL, Zhang YD, Reimers KJ, Packard PT, Astwood JD. 2009b. Potential national productivity implications of calorie and sodium reductions in the American diet. Am J Health Promot 23: 423–30.
- Davidson PM, Taylor TM. 2007. Chemical preservatives and natural antimicrobial compounds. In: MP Doyle, LR Beuchat, editors. Food microbiology: fundamentals and frontiers. Washington , D.C. : ASM Press. p 713–45.
- Desmond E. 2007. Reducing salt in meat and poultry products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 233–55.
- Devlieghere F, Geeraard F, Versyck KJ, Vandewaetere B, Van Impe J, Debevere J. 2001. Growth of Listeria monocytogenes in modified atmosphere packed cooked meat products: a predictive model. Food Microbiol 18: 53–66.
- Devlieghere F, Vermeiren L, Bontenbal E, Lamers PP, Debevere J. 2009. Reducing salt intake from meat products by combined use of lactate and diacetate salts without affecting microbial stability. Int J Food Sci Technol 44: 337–41.
- Dickinson BD, Havas S. 2007. Reducing the population burden of cardiovascular disease by reducing sodium intake: a report of the Council on Science and Public Health. Arch Intern Med 167: 1460–8.
- Dickinson KM, Keogh JB, Clifton P. 2009. Effects of a low-salt diet on flow-mediated dilation in humans. Am J Clin Nutr 89: 485–90.
-
Doores S. 2005. Organic acids. In: PM Davidson,
JN Sofos,
AL Branen, editors. Antimicrobials in food.
New York
: Taylor & Francis. p
91–142.
10.1201/9781420028737.ch4 Google Scholar
- Doyle MP, Roman D. 1982. Response of Campylobacter jejuni to sodium chloride. Appl Environ Microbiol 43: 561–5.
- Duché O, Trémoulet F, Glaser P, Labadie J. 2002. Salt stress proteins induced in Listeria monocytogenes. Appl Environ Microbiol 68: 1491–8.
- Elliott P, Walker L, Little MP, Blair-West JR, Shade RE, Lee R, Rouquet P, Leroy E, Jeunemaitre X, Ardaillou R, Paillard F, Meneton P, Denton DA. 2007. Change in salt intake affects blood pressure of chimpanzees—implications for human populations. Circulation 116: 1563–8.
- Frassetto LA, Morris RC, Sebastian A. 2007. Dietary sodium chloride intake independently predicts the degree of hyperchloremic metabolic acidosis in healthy humans consuming a net acid-producing diet. Am J Physiol-Renal Physiol 293: F521–5.
- Frings-Meuthen P, Baecker N, Heer M. 2008. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 23: 517–24.
- Fulladosa E, Serra X, Gou P, Arnau J. 2009. Effects of potassium lactate and high pressure on transglutaminase restructured dry-cured hams with reduced salt content. Meat Sci 82: 213–8.
- Fung TT, Chiuve SE, McCullough ML, Rexrode KM, Logroscino G, Hu FB. 2008. Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women. Arch Intern Med 168: 713–20.
- Geleijnse JM, Witteman JC, Stijnen T, Kloos MW, Hofman A, Grobbee DE. 2007. Sodium and potassium intake and risk of cardiovascular events and all-cause mortality: the Rotterdam Study. Eur J Epidemiol 22(11): 763–70.
- Gibson AM, Roberts TA. 1986. The effect of pH, water activity, sodium nitrite and storage temperature on the growth of enteropathogenic Escherichia coli and salmonellae in a laboratory medium. Int J Food Microbiol 3: 183–94.
- Gibson AM, Ellis-Brownlee RCL, Cahill ME, Szabo EA, Fletcher GC, Bremer PJ. 2000. The effect of 100% CO2 on the growth of nonproteolytic Clostridium botulinum at chill temperatures. Int J Food Microbiol 54: 39–48.
- Glass KA, McDonnell LM, Rassel RC, Zierke KL. 2007a. Controlling Listeria monocytogenes on sliced ham and turkey products using benzoate, propionate, and sorbate. J Food Prot 70: 2306–12.
- Glass K, Preston D, Veesenmeyer J. 2007b. Inhibition of Listeria monocytogenes in turkey and pork-beef bologna by combinations of sorbate, benzoate, and propionate. J Food Prot 70: 214–7.
- Gordon A, Barbut S. 1992. Mechanisms of meat batter stabilization. Crit Rev Food Sci Nutr 32: 299–332.
- Guardia MD, Guerrero L, Gelabert J, Gou P, Arnau J. 2006. Consumer attitude towards sodium reduction in meat products and acceptability of fermented sausages with reduced sodium content. Meat Sci 73: 484–90.
- Guinee TP, O'Kennedy BT. 2007. Reducing salt in cheese and dairy spreads. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 316–57.
- Gupta S, Ravishankar S. 2005. A comparison of the antimicrobial activity of garlic, ginger, carrot, and turmeric pastes against Escherichia coli O157:H7 in laboratory buffer and ground beef. Foodborne Pathog Dis 2: 330–40.
- He FJ, MacGregor GA. 2002. Effect of modest salt reduction on blood pressure: a meta-analysis of randomized trials. Implications for public health. J Human Hypertens 16: 761–70.
-
He FJ,
MacGregor GA. 2007. Dietary salt, high blood pressure and other harmful effects on health. In: D Kilcast,
F Angus, editors. Reducing salt in foods.
Boca Raton
,
Fla.
: CRC Press. p
18–54.
10.1533/9781845693046.1.18 Google Scholar
- He FJ, MacGregor GA. 2009. A comprehensive review on salt and health and current experience of worldwide salt reduction programmes. J Human Hyperten 23: 363–84.
- He FJ, Marciniak M, Visagie E, Markandu ND, Anand V, Dalton RN MacGregor GA. 2009a. Effect of modest salt reduction on blood pressure, urinary albumin, and pulse wave velocity in white, black, and Asian mild hypertensives. Hypertension 54: 482–8.
- He J, Gu DF, Chen J, Jaquish CE, Rao DC, Hixson JE, Chen JC, Duan XF, Huang JF, Chen CS, Kelly TN, Bazzano LA, Whelton PK. 2009b. Gender difference in blood pressure responses to dietary sodium intervention in the Gensalt study. J Hyperten 27: 48–54.
- Heaney RP. 2006. Role of dietary sodium in osteoporosis. J Am Coll Nutr 25: 271S–6S.
- Hoffmann IS, Cubeddu LX. 2009. Salt and the metabolic syndrome. Nutr Metab Cardiovasc Dis 19: 123–8.
- Hoffmann IS, Alfieri AB, Cubeddu LX. 2008. Salt-resistant and salt-sensitive phenotypes determine the sensitivity of blood pressure to weight loss in overweight/obese patients. J Clin Hyperten 10: 355–61.
- Hollenberg NK. 2006. The influence of dietary sodium on blood pressure. J Am Coll Nutr 25: 240S–6S.
- [ICRG] Intersalt Cooperative Research Group. 1988. Intersalt: an international study of electrolyte excretion and blood pressure. Brit Med J 297: 319–28.
- [IOM] Inst. of Medicine. 2004. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington , D.C. : Natl. Academies Press.
- Johanningsmeier S, McFeeters RF, Fleming HP, Thompson RL. 2007. Effects of Leuconostoc mesenteroides starter culture on fermentation of cabbage with reduced salt concentrations. J Food Sci 72: M166–72.
- Johnson ME, Kapoor R, McMahon DJ, McCoy DR, Narasimmon RG. 2009. Reduction of sodium and fat levels in natural and processed cheeses: scientific and technological aspects. Compr Rev Food Sci Food Saf 8: 252–68.
- Kilcast D, Den Ridder C. 2007. Sensory issues in reducing salt in food products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 201–20.
- Kremer S, Mojet J, Shimojo R. 2009. Salt reduction in foods using naturally brewed soy sauce. J Food Sci 74(6): S255–62.
- Laatikainen T, Pietinen P, Valsta L, Sundvall J, Reinivuo H, Tuomilehto J. 2006. Sodium in the Finnish diet: 20-year trends in urinary sodium excretion among the adult population. Eur J Clin Nutr 60: 965–70.
- Lado BH, Yousef AE. 2007. Characteristics of Listeria monocytogenes important to food processors. In: ET Ryser, EH Marth, editors. Listeria, listeriosis and food safety. Boca Raton , Fla. : CRC Press. p 157–213.
- Larsen R, Elvevoll EO. 2008. Water uptake, drip losses and retention of free amino acids and minerals in cod (Gadus morhua) fillet immersed in NaCl or KCl. Food Chem 107: 369–76.
- Larson AE, Johnson EA, Nelson JH. 1999. Survival of Listeria monocytogenes in commercial cheese brines. J Dairy Sci 82: 1860–8.
- Lawrence G, Salles C, Septier C, Busch J, Thomas-Danguin T. 2009. Odour-taste interactions: a way to enhance saltiness in low-salt content solutions. Food Qual Prefer 20: 241–8.
- Ley JP. 2008. Masking bitter taste by molecules. Chemosens Percept 1: 58–77.
- Lin PH, Ginty F, Appel LJ, Aickin M, Bohannon A, Garnero P, Barclay D, Svetkey LP. 2003. The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults. J Nutr 133: 3130–6.
- Lynch EJ, Dal Bello F, Sheehan EM, Cashman KD, Arendt EK. 2009. Fundamental studies on the reduction of salt on dough and bread characteristics. Food Res Int 42: 885–91.
- Man CMD. 2007. Technological functions of salt in food products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 157–73.
- Manabe M. 2008. Saltiness enhancement by the characteristic flavor of dried bonito stock. J Food Sci 73: S321–5.
- Marshall BJ, Ohye DF, Christian JH. 1971. Tolerance of bacteria to high concentrations of NaCl and glycerol in growth medium. Appl Microbiol 21: 363–4.
- Mattes RD, Donnelly D. 1991. Relative contributions of dietary-sodium sources. J Am Coll Nutr 10: 383–93.
- McCaughey S. 2007. Dietary salt and flavor: mechanisms of taste perception and physiological controls. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 77–98.
- McClure PJ, Roberts TA, Oguru PO. 1989. Comparison of the effects of sodium chloride, pH and temperature on the growth of Listeria monocytogenes on gradient plates and in liquid medium. Lett Appl Microbiol 9: 95–9.
- McGregor R. 2007. The use of bitter blockers to replace salt in food products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 221–32.
- Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, Griffin PM, Tauxe RV. 1999. Food-related illness and death in the United States. Emerg Infect Dis 5: 607–25.
- Moreau L, Bindzus W, Hill S. 2009. Influence of sodium chloride on color development of cereal model systems through changes in glass transition temperature and water retention. Cereal Chem 86: 232–8.
- Morris RC, Schmidlin O, Frassetto LA, Sebastian A. 2006. Relationship and interaction between sodium and potassium. J Am Coll Nutr 25: 262S–70S.
- Nadarajah D, Han JH, Holley RA. 2005a. Use of mustard flour to inactivate Escherichia coli O157:H7 in ground beef under nitrogen flushed packaging. Int J Food Microbiol 99: 257–67.
- Nadarajah D, Han JH, Holley RA. 2005b. Inactivation of Escherichia coli O157:H7 in packaged ground beef by allyl isothiocyanate. Int J Food Microbiol 99: 269–79.
- Nummer BA, Andress EL. 2002. Curing and smoking meats for home food preservation. Literature review and critical preservation points. 2002. Athens , Ga. : The Univ. of Georgia, Cooperative Extension Service. Available from: http//www.uga.edu/nchfp/publications/nchfp/lit_rev/cure_smoke_intro.html . Accessed 2009.
- Obligado SH, Goldfarb DS. 2008. The association of nephrolithiasis with hypertension and obesity: a review. Am J Hyperten 21: 257–64.
- Ohye DF, Christian JHB. 1967. Combined effects of temperature, pH, and water activity on growth and toxin production by Clostridium botulinum types A, B, and E. In: M Ingram, TA Roberts, editors. Botulism , 1966. London , U.K. : Chapman and Hall. p 217–23.
- Palar K, Sturm R. 2009. Potential societal savings from reduced sodium consumption in the U.S. adult population. Am J Health Promot 24(1): 49–57.
- Park JN, Hwang KT, Kim SB, Kim SZ. 2009. Partial replacement of NaCl by KCl in salted mackerel (Scomber japonicus) fillet products: effect on sensory acceptance and lipid oxidation. Int J Food Sci Technol 44: 1572–8.
- Pedro S, Nunes ML. 2007. Reducing salt in seafood products. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 256–82.
- Pimenta E, Gaddam KK, Oparil S, Aban I, Husain S, Dell'Italia LJ, Calhoun DA. 2009. Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. Hypertension 54: 475–81.
- Pitt JI, Miscamble BF. 1995. Water relations of Aspergillus flavus and closely related species. J Food Prot 58: 86–90.
- Pitt JI, Richardson KC. 1973. Spoilage by preservative-resistant yeast. CSIRO Food Res Q 33: 80–5.
- Pszczola DE. 2007. Savoring the possibilities. Food Technol 61(4): 55–66.
- Purdy J, Armstrong G. 2007. Dietary salt and the consumer. In: D Kilcast, F Angus, editors. Reducing salt in foods. Boca Raton , Fla. : CRC Press. p 99–123.
- Raybaudi-Massilia RM, Mosqueda-Melgar J, Martin-Belloso O. 2006. Antimicrobial activity of essential oils on Salmonella Enteritidis, Escherichia coli, and Listeria innocua in fruit juices. J Food Prot 69: 1579–86.
- Reddy KA, Marth EH. 1991. Reducing the sodium content of foods—a review. J Food Prot 54: 138–50.
- Reddy KA, Marth EH. 1995. Lactic-acid bacteria in Cheddar cheese made with sodium chloride, potassium chloride or mixtures of the two salts. J Food Prot 58: 62–9.
- Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, Obarzanek E, Conlin PR, Miller ER 3rd, Simons-Morton DG, Karanja N, Lin PH. 2001. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med 344: 3–10.
- Saint-Eve A, Lauverjat C, Magnan C, Déléris I, Souchon I. 2009. Reducing salt and fat content: impact of composition, texture and cognitive interactions on the perception of flavored model cheeses. Food Chem 116: 167–75.
- Schmidlin O, Forman A, Sebastian A, Morris RC. 2007. What initiates the pressor effect of salt in salt-sensitive humans? Observations in normotensive blacks. Hypertension 49: 1032–9.
- Schoene F, Mnich K, Jahreis G, Kinast C, Greiling A, Kirmse R, Hartung H, Leiterer M. 2009. Analysis of meat products, produced with mineral salt constituents and sensory assessment of meat articles produced with a mineral salt compared with common salt. Fleischwirtschaft 89: 149–52.
- Schoppen S, Pérez-Granados AM, Carbajal A, Sarriá B, Navas-Carretero S, Vaquero MP. 2008. Sodium-bicarbonated mineral water decreases aldosterone levels without affecting urinary excretion of bone minerals. Int J Food Sci Nutr 59: 347–55.
- Scott WJ. 1953. Water relations of Staphylococcus aureus at 30 °C. Austr J Biol Sci 6: 549–64.
- Sebastian A, Frassetto LA, Sellmeyer DE, Merriam RL, Morris RC. 2002. Estimation of the net acid load of the diet of ancestral preagricultural Homo sapiens and their hominid ancestors. Am J Clin Nutr 76: 1308–16.
- Seman DL, Borger AC, Meyer JD, Hall PA, Milkowski AL. 2002. Modeling the growth of Listeria monocytogenes in cured ready-to-eat processed meat products by manipulation of sodium chloride, sodium diacetate, potassium lactate, and product moisture content. J Food Prot 65: 651–8.
- Seman DL, Quickert SC, Borger AC, Meyer JD. 2008. Inhibition of Listeria monocytogenes growth in cured ready-to-eat meat products by use of sodium benzoate and sodium diacetate. J Food Prot 71: 1386–92.
- Stein LJ, Cowart BJ, Beauchamp GK. 2006. Salty taste acceptance by infants and young children is related to birth weight: longitudinal analysis of infants within the normal birth weight range. Eur J Clin Nutr 60: 272–9.
- Stopforth JD, Sofos JN, Busta FF. 2005. Sorbic acid and sorbates. In: PM Davidson, JN Sofos, AL Branen, editors. Antimicrobials in food. New York : Taylor & Francis. p 49–90.
- Tanaka N, Traisman E, Plantinga P, Finn L, Flom W, Meske L, Guggisberg J. 1986. Evaluation of factors involved in antibotulinal properties of pasteurized process cheese spreads. J Food Prot 49: 526–31.
- Tapia De Daza MS, Villegas Y, Martinez A. 1991. Minimal water activity for growth of Listeria monocytogenes as affected by solute and temperature. Int J Food Microbiol 14: 333–7.
- Taubes G. 1998. The (political) science of salt. Science 281: 898–907.
- Teucher B, Dainty JR, Spinks CA, Majsak-Newman G, Berry DJ, Hoogewerff JA, Foxall RJ, Jakobsen J, Cashman KD, Flynn A, Fairweather-Tait SJ. 2008. Sodium and bone health: the impact of moderately high and low salt intakes on calcium metabolism in postmenopausal women. J Bone Miner Res 23: 1477–85.
- Thomson BM. 2009. Nutritional modelling: distributions of salt intake from processed foods in New Zealand. Brit J Nutr 102(5): 757–65.
- Van Boekel MAJS. 2008. Kinetic modeling of food quality: a critical review. Compr Rev Food Sci Food Saf 7: 144–58.
- Van Vliet BN, Montani JP. 2008. The time course of salt-induced hypertension, and why it matters. Int J Obes 32(Suppl 6): S35–47.
- Walker J, MacKenzie AD, Dunning J. 2007. Does reducing your salt intake make you live longer? Interact Cardiovasc Thorac Surg 6: 793–8.
- [WHO] World Health Organization. 2007. Reducing salt intake in populations. Geneva : WHO Document Production Services. Available from: http://www.who.int/dietphysicalactivity/reducingsaltintake_EN.pdf . Accessed March 2009.
- Wijnker JJ, Koop G, Lipmam LJA. 2006. Antimicrobial properties of salt (NaCl) used for the preservation of natural casings. Food Microbiol 23: 657–62.
- Xiong YL. 2007. Meat binding: emulsions and batters. Savoy , Ill. : American Meat Science Assn.